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默克密理博Science網(wǎng)絡(luò)講座:細(xì)胞死亡的多條通路

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細(xì)胞死亡的多條通路: 獲得對(duì)細(xì)胞凋亡,壞死和自噬的深刻認(rèn)識(shí)和最新視角
The Many Roads to Cell Death: Gaining a Practical Understanding of Apoptosis, Necrosis, and Autophagy
本文摘自:Science Mag

細(xì)胞死亡是生命周期的一部分。在近幾年,對(duì)于細(xì)胞死亡途徑的研究已經(jīng)戲劇化的轉(zhuǎn)變成對(duì)于非凋亡途徑的探索,包括壞死-凋亡和自噬,并且對(duì)凋亡通路的機(jī)制有了更深刻的認(rèn)識(shí)。目前已經(jīng)通過(guò)最前沿的技術(shù)進(jìn)行了新的研究和發(fā)現(xiàn),尤其是在細(xì)胞計(jì)數(shù)和細(xì)胞死亡特異性標(biāo)志物領(lǐng)域。在這個(gè)網(wǎng)絡(luò)課堂中,演講嘉賓將和大家一起討論細(xì)胞死亡通路的最新視角,包括每個(gè)通路特征性的分子標(biāo)志物和細(xì)胞的變化。在這個(gè)講座中,我們可以學(xué)到很實(shí)用的細(xì)胞計(jì)數(shù)為基礎(chǔ)的方法對(duì)細(xì)胞死亡通路進(jìn)行詳細(xì)的分析,還可以了解如何分析數(shù)據(jù)以更好的了解腫瘤等疾病的病理學(xué)機(jī)制,并為藥物研發(fā)篩選出新的靶標(biāo)。

本次講座已于2014年6月4日(周三)9:00 a.m.上線(xiàn),此后您仍可以注冊(cè)觀(guān)看錄播。

在這個(gè)網(wǎng)絡(luò)課堂中,演講嘉賓將會(huì)介紹:
1. 不同細(xì)胞死亡途徑的最新視角;
2. 展示他們?cè)诩?xì)胞死亡機(jī)制和影響研究中的最新數(shù)據(jù);
3. 講述研究細(xì)胞死亡通路的技術(shù);
4. 實(shí)時(shí)回答在線(xiàn)問(wèn)題(僅在線(xiàn)直播時(shí)間)。

關(guān)于演講嘉賓


John Abrams, Ph.D.
University of Texas Southwestern Medical Center
Dallas, TX

Dr. Abrams completed his Ph.D. at Stanford University in California after completing his undergraduate degree at Cornell University in Ithaca, New York. He joined the University of Texas Southwestern Medical Center in 1994 as an assistant professor in the Department of Cell Biology, becoming an associate professor in 2000 and program chair of the genetics and development graduate program in 2004. Dr. Abrams has been professor of cell biology since 2006; his research examines the in vivo molecular networks involved in cell death regulation and explores determinants of chromatin organization, using Drosophila as a model system. Dr. Abrams is an Ellison Foundation Scholar and a member on the Faculty of 1000. His publication record includes invited book chapters and many top international peer-reviewed journals; he also holds three patents.


William G. Telford, Ph.D.
National Institutes of Health
Bethesda, MD

Dr. William Telford received his Ph.D. in microbiology from Michigan State University in 1994, where his laboratory developed some of the earliest techniques for flow cytometric detection of apoptosis. He received his postdoctoral training in immunology at The University of Michigan Medical School, and was appointed assistant scientist at the Hospital for Special Surgery in New York City from 1997 to 1999. Dr. Telford became a staff scientist at the National Cancer Institute, National Institutes of Health in 1999, and is currently the director of the flow cytometry core laboratory in the NCI Experimental Transplantation and Immunology Branch. Dr. Telford’s main research interests include: instrument development, particularly in the area of novel solid state laser integration into flow cytometers; flow cytometric stem cell detection and characterization; and functional characterization of early apoptosis by flow and image cytometry.


Moderator: Tianna Hicklin, Ph.D.
Science/AAAS
Washington, DC

Dr. Hicklin studied biology at Colorado State University for her undergraduate education before earning a Ph.D. in neuroscience from the University of Colorado Anschutz Medical Campus. Prior to joining Science/AAAS, she worked as a science writer intern for the University of Colorado’s Office of Media and Public Relations in Denver, Colorado and for Brookhaven National Laboratory’s Media and Communications Office in Upton, New York. Dr. Hicklin is currently the assistant editor for the Science/AAAS Custom Publishing Office.

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