|
||||||||||||||||||||||||||||||||||
[發(fā)表評(píng)論] [本類其他產(chǎn)品] [本類其他供應(yīng)商] [收藏] |
![]() |
銷售商: 艾美捷科技有限公司 | 查看該公司所有產(chǎn)品 >> |
【中文名稱】:腫瘤壞死因子(配體)超族成員11 多克隆抗體
【英語(yǔ)名稱】:RANKL Polyclonal Antibody
【產(chǎn)品類型】:一抗
【供應(yīng)商】:Abbkine
【產(chǎn)品貨號(hào)】:ABP53135
【產(chǎn)品規(guī)格】:30ul/100ul/200ul
【背景資料】:TNFSF11 encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. Tumor necrosis factor ligand superfamily member 11 was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found.
蛋白別名為:TNFSF11; OPGL; RANKL; TRANCE; Tumor necrosis factor ligand superfamily member 11; Osteoclast differentiation factor; ODF; Osteoprotegerin ligand; OPGLReceptor activator of nuclear factor kappa-B ligand; RANKL; TNF-related activation-induced cytokine; TRANCE; CD254;基因ID為:8600;蛋白質(zhì)ID:O14788
【應(yīng)用類型】:WB,IHC-p,ELISA
補(bǔ)充:最優(yōu)的抗體稀釋比例需要基于客戶實(shí)驗(yàn)進(jìn)行優(yōu)化.建議的起始稀釋比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:20000. Not yet tested in other applications.
【免疫原】:合成多肽:the C-terminal region of human RANKL.
【來(lái)源宿主】:兔
【反應(yīng)性】:人,小鼠,大鼠
【保存建議】:廠家推薦藍(lán)冰運(yùn)輸.在發(fā)貨后能在-20℃保存1年.為最大限度的避免損失,請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心.我們建議使用前分裝以避免反復(fù)凍融.
本產(chǎn)品為液體形式,溶解于PBS緩沖液中,含50%甘油,0.5%BSA和0.02%疊氮化鈉.
【產(chǎn)品說(shuō)明】:點(diǎn)擊:腫瘤壞死因子(配體)超族成員11 多克隆抗體查看更詳細(xì)產(chǎn)品說(shuō)明,更多應(yīng)用、儲(chǔ)存、價(jià)格、貨期等信息請(qǐng)致電400-6800-868垂詢Abbkine中國(guó)區(qū)域授權(quán)總代理艾美捷科技有限公司。更多特色試劑盒、特色抗體以及特色試劑等產(chǎn)品評(píng)論,請(qǐng)點(diǎn)擊查看每日生物評(píng)論網(wǎng)站。
Abbkine致力于為全球生命科學(xué)研究和醫(yī)療發(fā)展提供最新的產(chǎn)品和技術(shù)。Abbkine設(shè)計(jì)、開(kāi)發(fā)、生產(chǎn)并銷售了一系列獨(dú)特的產(chǎn)品,包括生命科學(xué)領(lǐng)域研究相關(guān)的抗體、研究試劑以及細(xì)胞功能分析產(chǎn)品。Abbkine的產(chǎn)品為科學(xué)研究中的挑戰(zhàn)提供卓有成效的解決方案,從而為全球的科學(xué)家節(jié)省時(shí)間并提高研究效率。作為Abbkine的中國(guó)區(qū)域總代理,艾美捷科技有限公司憑借豐富的專業(yè)經(jīng)驗(yàn),將一如既往的為中國(guó)區(qū)域客戶提供Abbkine優(yōu)質(zhì)的產(chǎn)品和技術(shù)服務(wù)。
艾美捷科技有限公司品線覆蓋生物研究各個(gè)領(lǐng)域,主要包括:分子生物學(xué)(核酸蛋白研究工具、cDNA/RNA、轉(zhuǎn)染試劑、植物組培/細(xì)胞培養(yǎng)、生化試劑及試劑盒),試劑藥品(蛋白酶抑制劑、化合物、熒光染料/探針、動(dòng)物血清)、抗體(一抗、二抗、封閉血清), 蛋白及試劑盒(細(xì)胞因子/重組蛋白、細(xì)胞凋亡/代謝/損傷、表觀遺傳、天然免疫)等。艾美捷為您尋找并提供最優(yōu)的產(chǎn)品解決方案、最完備的物流服務(wù)、最及時(shí)的售后服務(wù)。如果您對(duì)上述產(chǎn)品線感興趣,請(qǐng)致電免費(fèi)服務(wù)熱線400-6800-868到艾美捷垂詢相關(guān)產(chǎn)品信息及完整實(shí)驗(yàn)解決方案。
產(chǎn)品標(biāo)簽:腫瘤壞死因子(配體)超族成員11,腫瘤壞死因子(配體)超族成員11ABP53135,Rabbit IgG (Light Chain Specific) Monoclonal Antibody,腫瘤壞死因子(配體)超族成員11 多克隆抗體,RANKL Polyclonal Antibody