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重組小鼠SHH
英文名稱:Recombinant Murine Sonic Hedgehog N-Terminus總訪問:213
國產(chǎn)/進口:國產(chǎn)半年訪問:2
產(chǎn)地/品牌:百奧萊博產(chǎn)品類別:分子生物學試劑
規(guī)       格:GS4755 最后更新:2025-5-14
貨       號:GS4755
CAS   號:
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產(chǎn)品名稱:重組小鼠SHH
英文名稱:Recombinant Murine Sonic Hedgehog N-Terminus
產(chǎn)品貨號:GS4755
產(chǎn)品規(guī)格:5μg

分子量:Approximately 19.8kDa,a single non-glycosylated polypeptide chain containing 176 amino acids.
儲存條件:冷凍(-20℃)

概述

Sonic hedgehog is one of three proteins in the mammalian signaling pathway family called hedgehog,the others being desert hedgehog(DHH)and indian hedgehog(IHH).As the hh homologues,SHH has been found to have the most critical roles in development.It acts as a morphogen involved in patterning many systems,including the limb and midline structures in the brain,spinal cord,the thalamus by the zona limitans intrathalamica and the teeth.There SHH undergoes auto-processing to generate a 20 kDa(residues 24 - 197)N-terminal signaling domain(SHH-N)and a 25 kDa(residues 198 - 462)C-terminal domain with no known signaling role.

使用說明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技術規(guī)格
 
外觀 Sterile Filtered White lyophilized(freeze-dried)powder.
純度 >95%by SDS-PAGE and HPLC analyses.
來源 Escherichia coli.
生物活性 Fully biologically active when compared to standard.The ED50 as determined by inducing alkaline phosphatase production of murine C3H10T1/2 cells is 0.5 - 1.0μg/ml.
成分 Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4.
內(nèi)毒素 Less than 1 EU/μg of rMuSHH as determined by LAL method.
復溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列 IVIGPGRGFG KRRHPKKLTP LAYKQFIPNV AEKTLGASGR YEGKITRNSE RFKELTPNYN PDIIFKDEEN TGADRLMTQR CKDKLNALAI SVMNQWPGVK LRVTEGWDED GHHSEESLHY EGRAVDITTS DRDRSKYGML ARLAVEAGFD WVYYESKAHI HCSVKAENSV AAKSGG


根據(jù)您的關注的重組小鼠SHH,重組Murine Sonic Hedgehog N-Terminus,Recombinant Murine Sonic Hedgehog N-Terminus,重組小鼠Murine Sonic Hedgehog N-Terminus,SHH, Murine,您可能還對以下產(chǎn)品有需求:



名稱:重組小鼠干擾素α2(IFN-α2)
貨號:JN0430
規(guī)格:10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達系統(tǒng)制備而成,目的基因編碼的Cys24-Glu190表達純化得來。

IFNA2/IFN-alpha 2質(zhì)量控制:>95%(還原性SDS-PAGE)

IFNA2/IFN-alpha 2制劑:凍干品

IFNA2/IFN-alpha 2保存
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個月。

IFNA2/IFN-alpha 2復溶
打開試劑管前請先離心。
復溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復溶后,請根據(jù)用量分裝凍存,避免反復凍融。

關于IFNA2/IFN-alpha 2
At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxyl-terminal end.

關注重組小鼠SHH,重組Murine Sonic Hedgehog N-Terminus,Recombinant Murine Sonic Hedgehog N-Terminus,重組小鼠Murine Sonic Hedgehog N-Terminus,SHH, Murine的同時,為您推薦更多您可能感興趣的產(chǎn)品:


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