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產品名稱:重組人Tie-1
英文名稱:Recombinant Human Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains 1
產品貨號:JN0594
產品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動物細胞表達系統(tǒng)制備而成,目的基因編碼的Ala22-Gln760在C端含有His標簽。
Tie-1質量控制:>95%(還原性SDS-PAGE)
Tie-1制劑:凍干品
Tie-1保存:
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個月。
Tie-1復溶:
打開試劑管前請先離心。
復溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復溶后,請根據用量分裝凍存,避免反復凍融。
關于Tie-1:
TIE-1 (Tyrosine Kinase with Ig and EGF Homology domains 1) and TIE-2/Tek comprise a receptor tyrosine kinase (RTK) subfamily. These receptors are expressed on endothelial and hematopoietic progenitor cells and play critical roles in angiogenesis, vasculogenesis and hematopoiesis. Human TIE-1 cDNA encodes a 1124 amino acid (aa) residue precursor protein with an 18aa signal peptide, a 727 aa extracellular domain and a 354 aa cytoplasmic domain. so far, two ligands have been described for TIE-2 [angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2)], but no ligand was found for TIE-1.
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