重組小鼠DR6(TNFRSF21)

特別提示：包括重組小鼠DR6(TNFRSF21)在內(nèi)，本公司的所有產(chǎn)品僅可用于科研實(shí)驗，嚴(yán)禁用于臨床醫(yī)療及其他非科研用途！

產(chǎn)品名稱：重組小鼠DR6(TNFRSF21)
英文名稱：Recombinant Mouse Death Receptor 6
產(chǎn)品貨號：JN0465
產(chǎn)品規(guī)格：10μg|50μg|500μg|1mg

本品由我們的哺乳動物細(xì)胞表達(dá)系統(tǒng)制備而成，目的基因編碼的Gln42-His349在C端含有Fc標(biāo)簽和His標(biāo)簽

DR6/TNFRSF21質(zhì)量控制：＞95%(還原性SDS-PAGE)

DR6/TNFRSF21制劑：凍干品

DR6/TNFRSF21保存：
凍干蛋白置于-20℃以下可長期保存，室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4～7℃保存2～7天，可分裝后置于-20℃保存三個月。

DR6/TNFRSF21復(fù)溶：
打開試劑管前請先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復(fù)溶后，請根據(jù)用量分裝凍存，避免反復(fù)凍融。

關(guān)于DR6/TNFRSF21：
Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may activate JNK and be involved in T-cell differentiation.It is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).

根據(jù)您的關(guān)注的重組小鼠DR6(TNFRSF21)，rTNFRSF21，重組Death Receptor 6，重組DR6，Recombinant Mouse Death Receptor 6，rDR6，rmTNFRSF21，重組小鼠Death Receptor 6，重組TNFRSF21，重組小鼠DR6，重組小鼠TNFRSF21，rmDR6，您可能還對以下產(chǎn)品有需求：


JN0428 重組人干擾素ω1(IFN-ω1) 10μg|50μg|500μg|1mg
JN0543 重組人富含半胱氨酸的酸性分泌蛋白(SPARC) 10μg|50μg|500μg|1mg
JN0555 重組人AGER(晚期糖基化終產(chǎn)物特異性受體) 10μg|50μg|500μg|1mg
JN0874 重組人生長阻滯和DNA損傷誘導(dǎo)45γ(GADD45G) 10μg|50μg|500μg|1mg
JN1049 重組人鈣網(wǎng)蛋白3(CRT3)(calreticulin-3) 10μg|50μg|500μg|1mg
JN1214 重組人結(jié)合珠蛋白(Haptoglobin) 10μg|50μg|500μg|1mg
JN1648 重組人CTLA-4(CD152) 10μg|50μg|500μg|1mg

關(guān)注重組小鼠DR6(TNFRSF21)，rTNFRSF21，重組Death Receptor 6，重組DR6，Recombinant Mouse Death Receptor 6，rDR6，rmTNFRSF21，重組小鼠Death Receptor 6，重組TNFRSF21，重組小鼠DR6，重組小鼠TNFRSF21，rmDR6的同時，為您推薦更多您可能感興趣的產(chǎn)品：



名稱：重組人TGFβ1(成纖維細(xì)胞生長因子β1)
貨號：JN0240
規(guī)格：10μg|50μg|500μg|1mg
本品由我們的哺乳動物表達(dá)系統(tǒng)制備，目的基因編碼的Ala279-Ser390表達(dá)純化而來。

TGFβ-1質(zhì)量控制：＞95%(還原性SDS-PAGE)。

TGFβ-1制劑：凍干品

TGFβ-1保存：
凍干蛋白可在-20℃長期保存，室溫也可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4～7℃保存2～7天。
復(fù)溶后建議分裝凍存在-20℃，可保存3個月，應(yīng)避免反復(fù)凍融。

TGFβ-1復(fù)溶：
1、試劑開蓋前請先離心。
2、復(fù)溶濃度應(yīng)大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復(fù)溶后根據(jù)使用量分裝保存，避免反復(fù)凍融。

關(guān)于TGFβ-1：
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.