【背景資料】:Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4. CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates.
【應用類型】:Western blotting (0.5-4 μg/ml). However, the optimal concentrations should be determined individually.
【來源宿主】:兔
【反應性】:經檢測驗證,可與人種屬來源的CCR3蛋白發(fā)生免疫反應。
【保存建議】:提供的CCR3抗體產品為100 μg 無色溶液,其濃度為0.5 mg/ml,溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中。請將該CCR3抗體產品置于-20 ℃冷凍保存,建議分裝使用以避免反復凍融。
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更詳細產品說明及價格請點擊CCR3抗體查詢或致電400-6800-868與BioVision中國區(qū)域授權總代理艾美捷科技有限公司垂詢。