ILK1抗體

【背景資料】：ILKs (Integrin-linked kinases) in combination with integrins and growth factors regulate cell survival, cell cycle, cell-cell adhesion and cell motility. ILK functions as a scaffold bridging the extra-cellular matrix (ECM) and growth factor receptors to the actin cytoskeleton through interactions with integrin, PINCH (which links ILK to the RTKs via Nck2), CH-ILKBP and affixin. ILK phosphorylates several cellular targets including Akt, GSK-3, myosin light chain 2, as well as affixin. These phosphorylation events are key regulatory steps in modulating the activities of the targets.

【應(yīng)用類型】：Western blotting (0.5-4 μg/ml), Immunohistochemistry (10-20 μg/ml, frozen & paraffin). However, the optimal concentrations should be determined individually. The antibody recognizes 59 kDa of ILK1 from samples of human, mouse, and rat origins. Reactivity to other species has not been determined.

【來源宿主】：兔

【反應(yīng)性】：經(jīng)檢測驗證，可與人、小鼠、大鼠種屬來源的ILK1蛋白 發(fā)生免疫反應(yīng)。

【保存建議】：提供的ILK1抗體 產(chǎn)品為100 μg 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中。請將該ILK1抗體 產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復(fù)凍融。

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者。BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力。包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細胞研究等領(lǐng)域。作為BioVision中國區(qū)域總代理，艾美捷與BioVision一道為研究者們提供最好、最新細胞生物學(xué)研究工具而不斷擴大產(chǎn)品及服務(wù)質(zhì)量。

更詳細產(chǎn)品說明及價格請點擊ILK1抗體 查詢或致電400-6800-868與BioVision中國區(qū)域授權(quán)總代理艾美捷科技有限公司垂詢。