MSH2抗體

【背景資料】：DNA mismatch repair genes have been found to be associated with hereditary nonpolyposis colorectal cancer (HNPCC). Inherited mutations in the MSH2 were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability suggests that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression.

【應(yīng)用類(lèi)型】：Western blotting (1-4 μg/ml), immunoprecipitation (15-25 μg/ml), and Immunohistochemistry (15-25 μg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the MSH2 of human, mouse, and rat origins. Reactivity to other species has not been tested.

【來(lái)源宿主】：兔

【反應(yīng)性】：經(jīng)檢測(cè)驗(yàn)證，可與人、小鼠、大鼠種屬來(lái)源的MSH2蛋白 發(fā)生免疫反應(yīng)。

【保存建議】：提供的MSH2抗體 產(chǎn)品為100 μg 無(wú)色溶液，其濃度為0.2 mg/ml，溶解于包含有50%甘油, 1% BSA和0.02% 疊氮鈉的PBS緩沖液中。請(qǐng)將該MSH2抗體 產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復(fù)凍融。

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者。BioVision在開(kāi)發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力。包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域。作為BioVision中國(guó)區(qū)域總代理，艾美捷與BioVision一道為研究者們提供最好、最新細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量。

更詳細(xì)產(chǎn)品說(shuō)明及價(jià)格請(qǐng)點(diǎn)擊MSH2抗體 查詢(xún)或致電400-6800-868與BioVision中國(guó)區(qū)域授權(quán)總代理艾美捷科技有限公司垂詢(xún)。