Phospho-Mek1/2抗體

【背景資料】：MAP kinase kinase 1 (Mek1), also known as mitogen activated protein kinase kinase, MAP kinase kinase, ERK kinase 1 or microtubule-associated protein 2 kinase, is a 43 kDa dual-specificity protein kinase that phosphorylates threonine and tyrosine residues on MAP kinases such as Erk 1 and 2. Mek1 and Mek2 are involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis. Mek1 and Mek2 are activated by phosphorylation on serine 218 and 222 by serine-threonine kinase, Raf-1, which is part of the p21ras signal transduction pathway.

【應(yīng)用類型】：Western blotting (1:200-1000) and immunocytochemistry (1:100-200). However, the optimal concentrations should be determined individually. The antibody recognizes 45 kDa phospho-Mek1/2 (Ser217/221). It does not detect the unphosphorylated protein.

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【反應(yīng)性】：經(jīng)檢測驗證，可與人、小鼠、大鼠種屬來源的Phospho-Mek1/2蛋白 發(fā)生免疫反應(yīng)。

【保存建議】：提供的Phospho-Mek1/2抗體 產(chǎn)品為100 μl 無色溶液，其濃度為0.5 mg/ml，溶解于包含有50%甘油, 1% BSA和0.02% 疊氮鈉的PBS緩沖液中。請將該P(yáng)hospho-Mek1/2抗體 產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復(fù)凍融。

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者。BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力。包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域。作為BioVision中國區(qū)域總代理，艾美捷與BioVision一道為研究者們提供最好、最新細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量。

更詳細(xì)產(chǎn)品說明及價格請點(diǎn)擊Phospho-Mek1/2抗體 查詢或致電400-6800-868與BioVision中國區(qū)域授權(quán)總代理艾美捷科技有限公司垂詢。