TLR2抗體

【背景資料】：The Toll-like receptor (TLR) family in mammalian comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Up-to-date, ten TLRs (TLR1-10) have been described. TLR2 is differentially expressed in human cells. CD14+ monocytes expressed the highest level of TLR2 followed by CD15+ granulocytes, and CD19+ B-cells. CD3+ T-cells and CD56+ NK cells did not express TLR2. The expression of TLR2 on different cell types is regulated by different immune response modifiers. For example, LPS, GM-CSF, IL-1, and IL-10 up regulate TLR2, whereas IL-4, IFN-gamma, and TNF down regulate TLR2 expression in monocytes.

【應(yīng)用類型】：Western blotting (0.5-4 μg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~86 kDa TLR2 in Jurkat cell lysate. Reactivity to other species has not been tested. Blocking peptide (Cat.# 3552RBP-50) is available separately.

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【反應(yīng)性】：經(jīng)檢測驗證，可與人、小鼠、大鼠、猴種屬來源的TLR2蛋白發(fā)生免疫反應(yīng)。

【保存建議】：提供的TLR2抗體產(chǎn)品為100 μg 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS (pH 7.2)緩沖液中。請將該TLR2抗體產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復(fù)凍融。

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者。BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力。包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域。作為BioVision中國區(qū)域總代理，艾美捷與BioVision一道為研究者們提供最好、最新細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量。

更詳細(xì)產(chǎn)品說明及價格請點擊TLR2抗體查詢或致電400-6800-868與BioVision中國區(qū)域授權(quán)總代理艾美捷科技有限公司垂詢。