TLR5抗體

【背景資料】：The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 and TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation and translocation of NFkB and suggests that these receptors are involved in mediating inflammatory responses. TLR6 is highly homologous to TLR1, and like other members of TLR family, it induces NFkB signaling upon activation. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages, and monocytes.

【應(yīng)用類(lèi)型】：Western blotting (0.5-4 μg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody recognizes ~97 kDa TLR5 in sample from human, mouse and rat origins. Reactivity to other species has not been tested. Blocking peptide (Cat.# 3555RBP-50) is available separately.

兔

【反應(yīng)性】：經(jīng)檢測(cè)驗(yàn)證，可與人、小鼠、大鼠種屬來(lái)源的TLR5蛋白發(fā)生免疫反應(yīng)。

【保存建議】：提供的TLR5抗體產(chǎn)品為100 μg 無(wú)色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞的PBS緩沖液中。請(qǐng)將該TLR5抗體產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復(fù)凍融。

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者。BioVision在開(kāi)發(fā)和研究細(xì)胞凋亡檢測(cè)分析、代謝檢測(cè)方面具有卓越的影響力。包括檢測(cè)各種檢測(cè)分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號(hào)轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域。作為BioVision中國(guó)區(qū)域總代理，艾美捷與BioVision一道為研究者們提供最好、最新細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量。

更詳細(xì)產(chǎn)品說(shuō)明及價(jià)格請(qǐng)點(diǎn)擊TLR5抗體查詢(xún)或致電400-6800-868與BioVision中國(guó)區(qū)域授權(quán)總代理艾美捷科技有限公司垂詢(xún)。