Wnt-6抗體

【背景資料】：Wnt gene family members, including Wnt-1 through Wnt-10, play a key role in regulating cellular growth and differentiation. Wnt-1 is a cysteine-rich, secreted glycoprotein that associates with cell membranes and likely functions as a key regulator of cellular adhesion. Wnt-1, which is essential for normal development of the embryonic nervous system, contributes to hyperplasia and tumorigenic progression when improperly expressed in mammary tissue. Wnt-3 is involved in tumorigenesis and Wnt-2 and Wnt-4 may be associated with abnormal proliferation in human breast tissue. Wnt-6 is involved in oncogenesis and is co-expressed with Wnt10 in colorectal cancer cell lines. The presence of cervical and breast cell carcinomas may indicate an over expression of Wnt-6.

【應用類型】：Western blotting (0.5-4 μg/ml), Immunohistochemistry (10-20 μg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 40-46 kDa Wnt-6 from rat origins. Reactivity to other species has not been tested.

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【反應性】：經(jīng)檢測驗證，可與人、小鼠、大鼠種屬來源的Wnt-6蛋白 發(fā)生免疫反應。

【保存建議】：提供的Wnt-6抗體 產(chǎn)品為100 μg 無色溶液，其濃度為0.5 mg/ml，溶解于包含有30%甘油, 0.5% BSA和0.01%硫柳汞 的PBS緩沖液中。請將該Wnt-6抗體 產(chǎn)品置于-20 ℃冷凍保存，建議分裝使用以避免反復凍融。

BioVision的公司總部在美麗的舊金山灣地區(qū)，它是全球生命科學公司的領導者。BioVision在開發(fā)和研究細胞凋亡檢測分析、代謝檢測方面具有卓越的影響力。包括檢測各種檢測分析試劑盒、相關特色抗體、重組蛋白及細胞因子和酶等多種產(chǎn)品，以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細胞凋亡研究、能量代謝、細胞/組織蛋白提取、氧化應激與損傷、代謝與肥胖癥、細胞增殖與毒性、信號轉(zhuǎn)導、干細胞研究等領域。作為BioVision中國區(qū)域總代理，艾美捷與BioVision一道為研究者們提供最好、最新細胞生物學研究工具而不斷擴大產(chǎn)品及服務質(zhì)量。

更詳細產(chǎn)品說明及價格請點擊Wnt-6抗體 查詢或致電400-6800-868與BioVision中國區(qū)域授權總代理艾美捷科技有限公司垂詢。