English | 中文版 | 手機版 企業(yè)登錄 | 個人登錄 | 郵件訂閱
當前位置 > 產(chǎn)品目錄 > 試劑 > 其他生物試劑 > 結(jié)腸癌腫瘤分子標志物檢測試劑盒
結(jié)腸癌腫瘤分子標志物檢測試劑盒
英文名稱:Colonic Neoplasms Molecular Marker Detection Kit總訪問:1297
國產(chǎn)/進口:進口半年訪問:10
產(chǎn)地/品牌:BioPharmSoft產(chǎn)品類別:其他生物試劑
規(guī)       格:BR-1101C 最后更新:2011-11-13
貨       號:
CAS   號:
參考報價:3735
立即詢價 電話咨詢
[發(fā)表評論] [本類其他產(chǎn)品] [本類其他供應(yīng)商] [收藏]
銷售商: 拜琺(上海)信息技術(shù)有限公司 查看該公司所有產(chǎn)品 >>
  • 產(chǎn)品介紹
  • 公司簡介

結(jié)腸癌腫瘤分子標志物檢測試劑盒

 貨號: BR-1101C       規(guī)格: 96 Assay      價格: ¥3735.00

Colonic Neoplasms Molecular Marker (ERBB2,MAP2K6 and PTPN11) Detection Kit
 
Description: The kit provides a means of performing Colonic Neoplasms detection method based on kinase activity assays. Three targets of molecular marker (MAP2K6 and MAPK1) are involved in Colonic Neoplasms. This kit includes Streptavidin Coated Plates and specific Substrate-Peptides (biotinylated peptide substrates) for detection of the activity of MAP2K6 and MAPK1 which indicate the prognosis of Colonic Neoplasms. Molecular Markers in Colonic Neoplasms


 

Disease Molecular Marker Gene ID Gene Disease Relation
Colonic Neoplasms MAP2K6 5608 therapeutic
Colonic Neoplasms MAPK1 5594 marker/mechanism

- Molecular markers for drug discovery and life science research (mechanism).


Peptide Core Sequence: 

Specific Substrate-Peptides for Colonic Neoplasms Molecular Marker

 

Molecular Marker Substrate-Peptide Residue Active Site Reaction_Type
MAP2K6  Peptides Mix Tyr-182 182 Phosphorylation
MAPK1  Peptides Mix Tyr-439 439 Phosphorylation


Label of Substrate-Peptides: Biotinylated.

Quality Control: The substrate peptide was selected using our Colonic Neoplasms Diagnosis Kit. The quality of the biotinylated peptide was evaluated by reverse-phase HPLC and by mass spectrometry.

Storage: 

Store at 4 °C, Avoid Freeze.


Background:

Dual specificity mitogen-activated protein kinase kinase 6 also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17. MAPKK 6 is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis. Mitogen-activated protein kinase 1, also known as MAPK1, p42MAPK, and ERK2, is an enzyme that in humans is encoded by the MAPK1 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
 
聯(lián)系方式:
業(yè)務(wù)手機:18221844720   電話:021-34315602  郵箱:biopharmsoft@sina.com
 

bio-equip.com
售后服務(wù)
相關(guān)視頻
資料下載
快速詢價登錄注冊在線詢價 (請留下您的聯(lián)系方式,以便供應(yīng)商聯(lián)系您)
* 姓  名:
* 地  區(qū):
* 單  位:
職  位:
* 手機/電話:
* E-mail:
請寄產(chǎn)品資料:
需要 不需要
請報價格:
需要報價 不需要報價
留  言:
驗證碼:
換一張
我希望獲得多家供應(yīng)商報價
發(fā)表評論在線評論(0條)
手機版:結(jié)腸癌腫瘤分子標志物檢測試劑盒
搜索本類產(chǎn)品

更多瀏覽該公司同類產(chǎn)品
您最近瀏覽過的產(chǎn)品
Copyright(C) 1998-2025 生物器材網(wǎng) 電話:021-64166852;13621656896 E-mail:info@bio-equip.com
立即詢價