Prostate Specific Cancer Antigen, Mouse Anti Human

Prostate Specific Cancer Antigen, Mouse Anti Human Shipping:Ice Packs Synonyms PSMA, Prostate Specific Cancer Antigen, PSM, FGCP, FOLH, GCP2, mGCP, GCPII, NAALAD1, NAALAdase, FOLH1, Glutamate carboxypeptidase 2, Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, N-acetylated-alpha-linked acidic dipeptidase I, Pteroylpoly-gamma-glutamate carboxypeptidase, Folylpoly-gamma-glutamate carboxypeptidase, Folate hydrolase 1, Prostate-specific membrane antigen, Cell growth-inhibiting protein 27. Type Mouse Anti Human Monoclonal. Introduction PSMA is a cancer antigen that is widely expressed as a noncovalent homodimer on the surface of prostate cancer cells, rather than on normal cells, therefore it is an interesting target to image prostate tissues when being used with radioactive antibodies. PSMA is expressed on the surface of novel blood vessels that nourish a broad range of other solid tumors. PSMA is a type II membrane protein with folate hydrolase activity produced by prostatic epithelium. PSMA expression is found in extraprostatic tissues, including small bowel and brain. Clone Pk1H7AT. Immunogen Anti-human PSMA mAb is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PSMA amino acids 117-351 purified from E. coli. Ig Subclass Mouse IgG1 heavy chain and κ light chain. Purification Method PSMA antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. >

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