HTRA2, Mouse Anti Human

HTRA2, Mouse Anti Human Shipping:Ice Packs Synonyms Serine protease HTRA2 mitochondrial, EC 3.4.21.108, High temperature requirement protein A2, HtrA2, Omi stress-regulated endoprotease, Serine proteinase OMI, Serine protease 25, OMI, PARK13, PRSS25. Type Mouse Anti Human Monoclonal. Introduction HtrA2 also called Omi is a mammalian serine protease at high temperatures and has a chaperone activity at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Mature HtrA2 consists of a putative transmembrane domain; an inhibitor of apoptosis protein (IAP)-binding motif; a single C-terminal PDZ domain that mediates protein-protein interactions. Recently, HtrA2 has known to contribute both to caspase-dependent and caspase-independent cell death. Clone P1B3AT. Immunogen Anti-human HTRA2 mAb is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HTRA2 amino acids 134-458 purified from E. coli. Ig Subclass Mouse IgG1 heavy chain and κ light chain. Purification Method HTRA2 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. Protein formulation 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. Storage Procedures For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.