重組人Resistin

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產(chǎn)品名稱：重組人Resistin(RETN)(脂肪因子抵抗素)(ADSF)(脂肪組織特異分泌因子)
英文名稱：Recombinant Human Adipose tissue-specific secretory factor
產(chǎn)品貨號(hào)：JN1037
產(chǎn)品規(guī)格：10μg|50μg|500μg|1mg

本品由我們的大腸桿菌表達(dá)系統(tǒng)制備而成，目的基因編碼的Lys19-Pro108在C端含有His標(biāo)簽。

Resistin/RETN質(zhì)量控制：＞95%(還原性SDS-PAGE)

Resistin/RETN制劑：凍干品

Resistin/RETN保存：
凍干蛋白置于-20℃以下可長(zhǎng)期保存，室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4～7℃保存2～7天，可分裝后置于-20℃保存三個(gè)月。

Resistin/RETN復(fù)溶：
打開試劑管前請(qǐng)先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請(qǐng)溶于ddH2O。
復(fù)溶后，請(qǐng)根據(jù)用量分裝凍存，避免反復(fù)凍融。

關(guān)于Resistin/RETN：
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of bad cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.

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名稱：重組人白介素IL-4(白細(xì)胞介素4)
貨號(hào)：JN0392
規(guī)格：10μg|50μg|500μg|1mg
本品由我們的哺乳動(dòng)物表達(dá)系統(tǒng)制備，目的基因編碼的His25-Ser153在C端含有His標(biāo)簽。

IL-4質(zhì)量控制：＞95%(還原性SDS-PAGE)。

IL-4制劑：凍干品

IL-4保存：
凍干蛋白可在-20℃長(zhǎng)期保存，室溫也可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4～7℃保存2～7天。
復(fù)溶后建議分裝凍存在-20℃，可保存3個(gè)月，應(yīng)避免反復(fù)凍融。

IL-4復(fù)溶：
1、試劑開蓋前請(qǐng)先離心。
2、復(fù)溶濃度應(yīng)大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復(fù)溶后根據(jù)使用量分裝保存，避免反復(fù)凍融。

關(guān)于IL-4：
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal cells. IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergic response.