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產(chǎn)品名稱:重組人線粒體凋亡誘導(dǎo)因子1(AIFM1)
英文名稱:Recombinant Human Apoptosis-Inducing Factor 1, Mitochondrial
產(chǎn)品貨號(hào):JN0674
產(chǎn)品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達(dá)系統(tǒng)制備而成,目的基因編碼的Glu121-Asp613在N端含有His標(biāo)簽。
AIFM1質(zhì)量控制:>95%(還原性SDS-PAGE)
AIFM1制劑:凍干品
AIFM1保存:
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個(gè)月。
AIFM1復(fù)溶:
打開試劑管前請(qǐng)先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請(qǐng)溶于ddH2O。
復(fù)溶后,請(qǐng)根據(jù)用量分裝凍存,避免反復(fù)凍融。
關(guān)于AIFM1:
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces parthanatos i.e., caspase-independent fragmentation of chromosomal DNA. AIFM1 interacts with EIF3G, and thereby inhibits the EIF3 machinery and protein synthesis, and activates casapse-7 to amplify apoptosis. It binds to DNA in a sequence-independent manner and plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells.
根據(jù)您的關(guān)注的
重組人線粒體凋亡誘導(dǎo)因子1(AIFM1),重組人Apoptosis-Inducing Factor 1, Mitochondrial,重組線粒體凋亡誘導(dǎo)因子1,重組Apoptosis-Inducing Factor 1, Mitochondrial,rhAIFM1,重組AIFM1,重組人AIFM1,重組人線粒體凋亡誘導(dǎo)因子1,Recombinant Human Apoptosis-Inducing Factor 1, Mitochondrial,rAIFM1,您可能還對(duì)以下產(chǎn)品有需求:
名稱:重組人血小板生成素(帶His標(biāo)簽)
貨號(hào):JN0268
規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動(dòng)物表達(dá)系統(tǒng)制備,目的基因編碼的Ser22-Gly353在N端和C端都含有His標(biāo)簽
Thrombopoietin/TPO質(zhì)量控制:>95%(還原性SDS-PAGE)。
Thrombopoietin/TPO制劑:凍干品
Thrombopoietin/TPO保存:
凍干蛋白可在-20℃長期保存,室溫也可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天。
復(fù)溶后建議分裝凍存在-20℃,可保存3個(gè)月,應(yīng)避免反復(fù)凍融。
Thrombopoietin/TPO復(fù)溶:
1、試劑開蓋前請(qǐng)先離心。
2、復(fù)溶濃度應(yīng)大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復(fù)溶后根據(jù)使用量分裝保存,避免反復(fù)凍融。
關(guān)于Thrombopoietin/TPO:
Thrombopoietin (TPO) is a glycoprotein hormone which belongs to the EPO/TPO family. It produced by the liver and kidney which regulates the production of platelets. TPO stimulates the production and differentiation of megakaryocytes, the bone marrow cells that bud off large numbers of platelets. Lineage-specific cytokine affects the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
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關(guān)注
重組人線粒體凋亡誘導(dǎo)因子1(AIFM1),重組人Apoptosis-Inducing Factor 1, Mitochondrial,重組線粒體凋亡誘導(dǎo)因子1,重組Apoptosis-Inducing Factor 1, Mitochondrial,rhAIFM1,重組AIFM1,重組人AIFM1,重組人線粒體凋亡誘導(dǎo)因子1,Recombinant Human Apoptosis-Inducing Factor 1, Mitochondrial,rAIFM1的同時(shí),為您推薦更多您可能感興趣的產(chǎn)品:
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