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銷售商: 艾美捷科技有限公司 | 查看該公司所有產(chǎn)品 >> |
【背景資料】:The caspase family of cysteine proteases plays a key role in apoptosis. Caspase-7, also known as Mch3α, ICE/LAP3 and CMH1, is a 34 kDa protein that is activated during Fas- and TNF-induced apoptosis. Caspase-7 has been identified as a major contributor to the execution phase of cellular apoptosis. It cleaves essential cellular machinery following its own cleavage from an inactive proenzyme to an active heterodimeric form. Caspase-7 is processed by caspase-3, -6, -8, -9, and –10 as well as by Granzyme B.
【應(yīng)用類型】:Western blot analysis (0.5-2 μg/ml) and immunoprecipitation (4-10 μg/ml). However the optimal conditions should be determined individually. Detects both pro-caspase-7 (34 kDa) and the large subunit of cleaved caspase-7 (19 kDa) in apoptosis cells on SDS-PAGE immunoblots.
【來源宿主】:小鼠
【反應(yīng)性】:經(jīng)檢測驗(yàn)證,可與人、小鼠、大鼠種屬來源的Caspase-7蛋白發(fā)生免疫反應(yīng)。
【保存建議】:提供的Caspase-7抗體產(chǎn)品為100 μg 無色溶液,其濃度為0.5 mg/ml,溶解于包含有1 mg/ml BSA和1.5 mM硫柳汞和50%甘油的PBS緩沖液中。請將該Caspase-7抗體產(chǎn)品置于-20 ℃冷凍保存,建議分裝使用以避免反復(fù)凍融。
BioVision的公司總部在美麗的舊金山灣地區(qū),它是全球生命科學(xué)公司的領(lǐng)導(dǎo)者。BioVision在開發(fā)和研究細(xì)胞凋亡檢測分析、代謝檢測方面具有卓越的影響力。包括檢測各種檢測分析試劑盒、相關(guān)特色抗體、重組蛋白及細(xì)胞因子和酶等多種產(chǎn)品,以及其他創(chuàng)新的研究工具。其產(chǎn)品覆蓋細(xì)胞凋亡研究、能量代謝、細(xì)胞/組織蛋白提取、氧化應(yīng)激與損傷、代謝與肥胖癥、細(xì)胞增殖與毒性、信號轉(zhuǎn)導(dǎo)、干細(xì)胞研究等領(lǐng)域。作為BioVision中國區(qū)域總代理,艾美捷與BioVision一道為研究者們提供最好、最新細(xì)胞生物學(xué)研究工具而不斷擴(kuò)大產(chǎn)品及服務(wù)質(zhì)量。
更詳細(xì)產(chǎn)品說明及價(jià)格請點(diǎn)擊Caspase-7抗體查詢或致電400-6800-868與BioVision中國區(qū)域授權(quán)總代理艾美捷科技有限公司垂詢。