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Enzyme |
Target |
Assay |
|
Kinase |
ABL1s, ACK, AKTs, AMPKs, Auroras, AXL, BRK, BXM, CAMKs, CDKs, CyclinA2, DAPK1, EGFRs, ERKs, FAK, FGFR, FLT, GRK, GSKs, HER, HIPK, IKKs, JNKs, LYN B, MAPKAPK2/3/5, p38s, ROCKs, SLK, TNIK, ULK1, VRK2, ZAK,et al. |
ADP-Glo |
|
Methyl-lysine |
CBX1, L3MBTL1 |
AlphaScreen/Fluorogenic |
|
Heat shock protein |
HSP90α, HSP90ß |
AlphaScreen |
|
Deacetylases |
HDAC1/2/3/4/5/6/7/8/9, SIRT1/2/3/5 |
Fluorogenic |
|
PARPs |
PARP1/2/3/6/7/10/11/14/15, TNKS1/S2 |
Chemiluminescence/Colorimetric |
|
Protease |
DPP3/4/7/8/9, FAP , POP, Renin, Caspase3/6/7/8 |
Fluorogenic |
|
Phosphodiesterase |
PDEs, Autotaxin |
TR-FRET/ FP / Fluorogenic |
|
Demethylases |
FBXL10/11, JARID1A/B/C/D, JMJD1A, JMJD2s, JMJD3, LSD1, PHF8, TET1, TET2, UTX |
AlphaScreen /Chemiluminescent |
|
Methyltransferases |
DNMTs, DOT1L, EHMT1/GLP, EZHs, G9a, Histones , MLL1, NSDs, PRMTs, SetDB1, SUV39H, SMYDs, SETs,et al. |
Chemiluminescence |
|
Bromodomains |
ATADs, BAZ2B, BPTF/FALZ, BRD1/2/3/4/9, BRPF3, CECR2, CREBBP, BACE1, SMARCA2/4, BRG1, BRM, CBP,et al. |
TR-FRET/AlphaScreen |
|
Immnotherapy related |
ARG, CD, CTLA4, GITRL, IDO, MAT2A, NAMPT, PD-1, TDO, TIGIT, TPH,et al. |
Colorimetric/Fluorogenic |
|
Others |
COX, Myeloperoxidase, FAAH, FABP4 , HAT, Lipoxygenase , PAD, PAF Acetylhydrolase , sPLA2 (Type V), PPARγ,et al. |
FP/colorimetric /Fluorogenic |
