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231 次 小鼠主動脈應(yīng)力激活平滑肌細胞適應(yīng)性程序維持強度防動脈瘤和夾層 2025-6-30
Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in MiceKeywords: aort
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317 次 成骨細胞線粒體氧化應(yīng)激或自噬減少不足以模擬衰老對骨機械反應(yīng)性損害 2025-6-24
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsivenessKeywords:
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182 次 苔蘚抑素-1（Bryostatin-1）通過抑制內(nèi)皮細胞自噬改善動脈功能 2025-6-24
Bryostatin-1 improves function in arteries with suppressed endothelial cell autophagyKeywords: Aging; Bryostatin-1; Endothelial cell; Nitric oxide.內(nèi)皮功能障礙是心血管衰老的標志，內(nèi)
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229 次 Piezo1 對抗與衰老相關(guān)的皮質(zhì)骨丟失 2025-6-24
Piezo1 opposes age-associated cortical bone lossKeywords: Piezo1; age-associated bone loss; endocortical bone resorption; mechanical stimulation.衰老會導致松質(zhì)骨和皮質(zhì)間隔的骨質(zhì)流失
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215 次 機械激活的間充質(zhì)衍生骨細胞通過細胞外囊泡介導的機制驅(qū)動血管生成 2025-6-23
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanismKeywords: Osteoblast; VEGF; angiogenesis; mechanobiology
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168 次 血管炎性疾病和內(nèi)皮表型 2025-6-17
Vascular Inflammatory Diseases and Endothelial PhenotypesKeywords: EC phenotypes; endothelial cell; inflammation; vascular diseases.內(nèi)皮細胞排列在管腔表面，充當分隔血液和周圍組織的
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133 次 微管蛋白乙酰化增強機械應(yīng)力下小梁網(wǎng)細胞的微管穩(wěn)定性 2025-6-16
Tubulin Acetylation Enhances Microtubule Stability in Trabecular Meshwork Cells Under Mechanical StressKeywords: trabecular meshwork, glaucoma, tubulin acetylation, mechanical stre
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307 次 拉伸誘導的內(nèi)皮細胞單層損傷的相關(guān)研究 2025-6-10
Stretch-induced damage in endothelial monolayersKeywords: Aging; Cell mechanics; Endothelium; Mechanobiology; Senescence; Stretch.由于血流的脈動性，包括流體剪切力、壓力和循環(huán)拉伸在
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345 次 視網(wǎng)膜神經(jīng)節(jié)細胞經(jīng)IL-12-SCGF-β串擾誘導干細胞衍生的神經(jīng)保護作用 2025-6-9
Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalkKWS：Retinal ganglion cells；stem cell；neuroprotection；IL-12；SCGF-β；cross
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401 次 血管內(nèi)皮-間充質(zhì)串擾通過 Notch 信號驅(qū)動人成骨細胞的成骨分化 2025-6-4
Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signalingKeywords: Co-culture; Endothelial cells; Notch signaling; Osteoblast
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335 次 TRPV4 抑制劑和機械負荷對減輕炎癥的協(xié)同作用 2025-6-3
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammationKeywords: anti-inflammatory phenotype; inhibition, mechanical loading; macrophage polarization; mi
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374 次 I 類 PI3Ks 激活小梁網(wǎng)細胞中拉伸誘導的自噬 2025-5-27
Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cellsKeywords: Autophagy; Glaucoma; Mechanical stress; PI3K; Primary cilia; Trabecular meshwork.眼壓升高（IO
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302 次 內(nèi)皮 IGFBP6 抑制血管炎癥和動脈粥樣硬化 2025-5-26
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosisKWS：IGFBP6；vascular inflammation；atherosclerosis動脈粥樣硬化通常發(fā)生在血流紊亂（DF）區(qū)域，例如動脈分支或彎
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370 次 c-REL串擾TXNIP-p38與非經(jīng)典NF-κB通路協(xié)調(diào)紊亂血流區(qū)動脈粥樣硬化 2025-5-20
Endothelial c-REL orchestrates atherosclerosis at regions of disturbed flow through crosstalk with TXNIP-p38 and non-canonical NF-κB pathwaysKWS：c-REL, Shear stress, Endothe
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343 次 動脈粥樣硬化中血流誘導的內(nèi)皮細胞重編程 2025-5-19
Flow-induced reprogramming of endothelial cells in atherosclerosisSubject terms: Cell biology, Systems biology動脈粥樣硬化是一種主要影響動脈的多因素慢性炎癥性疾病。內(nèi)皮細胞功能障礙
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364 次 E2F1誘導IL-6炎癥循環(huán)介導癌癥免疫，預測T細胞表型轉(zhuǎn)換和治療反應(yīng) 2025-5-13
E2F1-induced autocrine IL-6 inflammatory loop mediates cancer-immune crosstalk that predicts T cell phenotype switching and therapeutic responsivenessKeywords: CD4 +/CD8 + T cells;
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332 次 IL-33 經(jīng) OX40L 促進人肥大細胞誘導 CD4+ T 細胞產(chǎn)生 IL-9 2025-5-12
IL-33-primed human mast cells drive IL-9 production by CD4+ effector T cells in an OX40L-dependent mannerKeywords: IL-33; IL-9; OX40L; Th cell; mast cell.2 型免疫反應(yīng)是針對皮膚和粘
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382 次 運動減輕血流再循環(huán)激活代謝轉(zhuǎn)能器 SCD1 催化血管保護性代謝物 2025-5-7
Exercise mitigates flow recirculation and activates metabolic transducer SCD1 to catalyze vascular protective metabolitesKS：Exercise；flow recirculation；SCD1作為對周期性心臟收縮的
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359 次 靶向軟骨下骨骨細胞中的H19用于減輕骨關(guān)節(jié)炎軟骨降解 2025-5-6
Targeting Long Noncoding RNA H19 in Subchondral Bone Osteocytes and the Alleviation of Cartilage Degradation in OsteoarthritisKWS：LncRNA H19；Subchondral Bone Osteocytes；Cartilag
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417 次 內(nèi)皮雌激素-心肌cGMP軸決定壓力超負荷期間的血管生成和心臟功能 2025-4-28
Endothelial oestrogen-myocardial cyclic guanosine monophosphate axis critically determines angiogenesis and cardiac performance during pressure overloadKeywords: Angiogenesis; Cycl
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