61 次C/EBPβ 拮抗劑誘導(dǎo)巨噬細(xì)胞促炎極化增強(qiáng)抗腫瘤免疫 2025-7-3
The C/EBPβ antagonist peptide lucicebtide (ST101) induces macrophage polarization toward a pro-inflammatory phenotype and enhances anti-tumor immune responsesKeywords: C/EBP&b
260 次小鼠主動(dòng)脈應(yīng)力激活平滑肌細(xì)胞適應(yīng)性程序維持強(qiáng)度防動(dòng)脈瘤和夾層 2025-6-30
Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in MiceKeywords: aort
333 次成骨細(xì)胞線粒體氧化應(yīng)激或自噬減少不足以模擬衰老對骨機(jī)械反應(yīng)性損害 2025-6-24
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsivenessKeywords:
193 次苔蘚抑素-1(Bryostatin-1)通過抑制內(nèi)皮細(xì)胞自噬改善動(dòng)脈功能 2025-6-24
Bryostatin-1 improves function in arteries with suppressed endothelial cell autophagyKeywords: Aging; Bryostatin-1; Endothelial cell; Nitric oxide.內(nèi)皮功能障礙是心血管衰老的標(biāo)志,內(nèi)
246 次Piezo1 對抗與衰老相關(guān)的皮質(zhì)骨丟失 2025-6-24
Piezo1 opposes age-associated cortical bone lossKeywords: Piezo1; age-associated bone loss; endocortical bone resorption; mechanical stimulation.衰老會(huì)導(dǎo)致松質(zhì)骨和皮質(zhì)間隔的骨質(zhì)流失
342 次TRPV4 抑制劑和機(jī)械負(fù)荷對減輕炎癥的協(xié)同作用 2025-6-3
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammationKeywords: anti-inflammatory phenotype; inhibition, mechanical loading; macrophage polarization; mi