231 次小鼠主動脈應(yīng)力激活平滑肌細(xì)胞適應(yīng)性程序維持強度防動脈瘤和夾層 2025-6-30
Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in MiceKeywords: aort
317 次成骨細(xì)胞線粒體氧化應(yīng)激或自噬減少不足以模擬衰老對骨機械反應(yīng)性損害 2025-6-24
Mitochondrial oxidative stress or decreased autophagy in osteoblast lineage cells is not sufficient to mimic the deleterious effects of aging on bone mechanoresponsivenessKeywords:
182 次苔蘚抑素-1(Bryostatin-1)通過抑制內(nèi)皮細(xì)胞自噬改善動脈功能 2025-6-24
Bryostatin-1 improves function in arteries with suppressed endothelial cell autophagyKeywords: Aging; Bryostatin-1; Endothelial cell; Nitric oxide.內(nèi)皮功能障礙是心血管衰老的標(biāo)志,內(nèi)
230 次Piezo1 對抗與衰老相關(guān)的皮質(zhì)骨丟失 2025-6-24
Piezo1 opposes age-associated cortical bone lossKeywords: Piezo1; age-associated bone loss; endocortical bone resorption; mechanical stimulation.衰老會導(dǎo)致松質(zhì)骨和皮質(zhì)間隔的骨質(zhì)流失
215 次機械激活的間充質(zhì)衍生骨細(xì)胞通過細(xì)胞外囊泡介導(dǎo)的機制驅(qū)動血管生成 2025-6-23
Mechanically activated mesenchymal-derived bone cells drive vessel formation via an extracellular vesicle mediated mechanismKeywords: Osteoblast; VEGF; angiogenesis; mechanobiology
401 次血管內(nèi)皮-間充質(zhì)串?dāng)_通過 Notch 信號驅(qū)動人成骨細(xì)胞的成骨分化 2025-6-4
Endothelial-mesenchymal crosstalk drives osteogenic differentiation of human osteoblasts through Notch signalingKeywords: Co-culture; Endothelial cells; Notch signaling; Osteoblast
335 次TRPV4 抑制劑和機械負(fù)荷對減輕炎癥的協(xié)同作用 2025-6-3
Synergetic role of TRPV4 inhibitor and mechanical loading on reducing inflammationKeywords: anti-inflammatory phenotype; inhibition, mechanical loading; macrophage polarization; mi
374 次I 類 PI3Ks 激活小梁網(wǎng)細(xì)胞中拉伸誘導(dǎo)的自噬 2025-5-27
Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cellsKeywords: Autophagy; Glaucoma; Mechanical stress; PI3K; Primary cilia; Trabecular meshwork.眼壓升高(IO